Actively Recruiting
Home Rehabilitation Improves Cardiac Effort in Pulmonary Arterial Hypertension
Led by University of Rochester · Updated on 2025-09-10
55
Participants Needed
1
Research Sites
126 weeks
Total Duration
On this page
Sponsors
U
University of Rochester
Lead Sponsor
U
United Therapeutics
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate whether a home rehabilitation program for patients diagnosed with Pulmonary Arterial Hypertension (PAH) will decrease Cardiac Effort (number of heart beats used during 6-minute walk test/walk distance) and improve quality of life. Ultimately, this information could help improve the management of patients with PAH.
CONDITIONS
Official Title
Home Rehabilitation Improves Cardiac Effort in Pulmonary Arterial Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Follow patient care at University of Rochester Medical Center Pulmonary Hypertension Clinic
- Adults over 18 years old with right heart catheterization confirmed Pulmonary Arterial Hypertension
- On stable vasodilator medication dosing for at least 30 days with no planned changes during the 12-week study
- Access to a smartphone or email to receive daily messages, or willingness to use a provided smartphone during the study
- Clinically stable as assessed by the investigator, without ongoing improvement or worsening
- Approved by the treating investigator as safe to participate prior to enrollment
You will not qualify if you...
- Pregnancy
- Pulmonary Hypertension Groups 2 through 5
- Resting heart rate over 120 beats per minute during screening
- Inability to walk
- WHO Functional Class IV
- No access to email or text messaging
- Unable to follow daily instructions, including performing two home 6-minute walk tests during initial monitoring
- Currently participating in a self-reported rehabilitation or exercise program
- Using oxygen therapy exceeding 6 liters per minute at rest
- Exclusion at Principal Investigator's discretion
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Rochester Medical Center
Rochester, New York, United States, 14642
Actively Recruiting
Research Team
D
Daniel Lachant, DO
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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