Development of At-Home Transcutaneous Auricular Vagus Nerve Stimulation for Post-Stroke Rehabilitation

What this Trial Is About

Researchers are exploring the use of transcutaneous auricular vagus nerve stimulation (taVNS) combined with motor rehabilitation to improve upper limb function after stroke. Early studies suggest that applying electrical stimulation to the ear during motor rehabilitation may double the benefits by enhancing brain plasticity. This trial aims to test this innovative approach in a home setting, making the treatment more accessible, especially for those living in rural or remote areas. Participants will receive task-specific training paired with EMG-activated taVNS three times a week for two weeks at home. Before this home intervention, lab-based testing will validate the stimulation sensors to ensure they work properly for at-home use. The study focuses on assessing the safety, feasibility, and acceptability of self-administered taVNS for stroke survivors with unilateral upper limb weakness. During the study, researchers will monitor dropout rates, safety of stimulation, and compliance over the two-week period. Participants' subjective ratings of feasibility and motor function improvements will also be evaluated. The trial involves regular assessments to determine how well participants can follow the treatment plan and will help identify any challenges to expanding this technology in future larger trials.

At-Home taVNS - Stroke Rehab