Actively Recruiting
Home tDCS for the Treatment of Major Depression.
Led by Ionclinics & Deionic SL · Updated on 2026-05-01
198
Participants Needed
3
Research Sites
89 weeks
Total Duration
On this page
Sponsors
I
Ionclinics & Deionic SL
Lead Sponsor
H
Hospital Universitari de Bellvitge
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this multicentric randomized controlled trial is to compare the effectiveness and safety of home-based tDCS for the treatment of major depression versus tDCS treatment in a healthcare centre, and explore the effects of an accelerated home-tDCS protocol. The change in depression index at the end of treatment, measured with MADRS, will be the primary outcome.
CONDITIONS
Official Title
Home tDCS for the Treatment of Major Depression.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Spanish or Catalan speakers of both sexes between the ages of 18 and 65
- Diagnosed with major depression or bipolar disorder type 1 or 2 based on DSM-5 criteria
- Have a moderate or higher score (15 or above) on the Montgomery-5berg Depression Rating Scale (MADRS)
- May be receiving pharmacological treatment for depression or not
- Able and willing to commit to supervision and safety monitoring during the study
- Able to properly apply home tDCS independently or with a companion's help
You will not qualify if you...
- Diagnosis of psychotic, schizoaffective, or personality disorders (cluster A and B)
- History of neurological disease, intellectual disability, or cognitive impairment
- Presence of metal implants, cochlear implants, pacemakers, brain stimulation in the last 6 months, or clinical/family history of epilepsy
- Dermatological problems like allergic skin reactions at electrode sites
- High risk of suicide as assessed by psychiatrist and Columbia Suicide Risk Scale
- Drug or alcohol abuse in the past 3 months (except nicotine)
- Changes in pharmacological or non-pharmacological treatments during the study or 3 months prior
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Hospital Universitario de Bellvitge
L'Hospitalet de Llobregat, Barcelona, Spain, 08304
Actively Recruiting
2
Hospital Universitari de Mataró
Mataró, Barcelona, Spain, 08304
Actively Recruiting
3
Parc Taulí Hospital Universitari
Sabadell, Barcelona, Spain, 08208
Not Yet Recruiting
Research Team
A
Ane Miren Gutiérrez Muto, PhD
CONTACT
E
Ensayos Ionclincs
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here