Home Use of Full-Body Stimulation Suits to Reduce Muscle Stiffness and Coordination Problems in People with Multiple Sclerosis
Led by Daphne Kos · Updated on 2026-02-06
70
Participants Needed
2
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying whether wearing a full-body electrical stimulation suit at home can help people with Multiple Sclerosis MS who experience muscle stiffness spasticity or poor coordination ataxia. The study compares two groups one using the stimulation suit alongside their usual care, and a control group receiving only their usual care. The purpose is to see if the suit reduces symptoms and improves daily functioning over six weeks.
Participants in the intervention group will wear the tailored electro-stimulation suit daily or every other day for six weeks, starting with one week at an MS center and continuing five weeks at home. The suit delivers low-energy electrical pulses to key muscle groups and is programmed specifically for each user by trained medical staff. The control group will receive their usual rehabilitation care without the suit.
Participants will undergo clinical tests at the MS center after one week and six weeks, including various physical and functional assessments like walking tests and muscle function scales. The study also collects weekly symptom ratings during the intervention. Researchers will measure changes in coordination, muscle stiffness, and overall physical ability, with safety monitoring throughout. The total participation lasts six weeks with scheduled evaluations.
CONDITIONS
Brief Title
At Home Use of Stimulation Suits for Managing MS Symptoms
Research Team
D
Daphne Kos
A
Alix-Anne Schreinemacher
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Presence of ataxia with a SARA score of 4 or higher, or spasticity with a MAS score of 1 or higher
Ability to understand instructions and complete questionnaires adequately
You will not qualify if you...
Presence of implanted medical devices such as pacemaker, Baclofen pump, neurostimulator, defibrillator, shunts, ECG equipment, electronic life support, or high frequency operation equipment
Change in disease modifying treatment within the last 3 months
Use of Botuline Toxine A within the last 3 months
Recent relapse within the last 3 months
Acute musculoskeletal problems that prevent test performance
Pregnancy
Body size larger than 3XL (triple extra large)
Skin eruptions or swollen, infected, or inflamed skin areas in the stimulation zone
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit
Implementation
Duration - 6 weeks
Participants in the stimulation suit group will wear a full-body neuromodulation suit every day or every other day for six weeks, in addition to their usual care. Participants in the usual care group will continue with their rehabilitation therapy without additional intervention.
Visits at week 1 and week 6 for assessments; weekly symptom assessments during the 6 weeks
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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Published Research Related To This Trial
The six spot step test is superior in detecting walking capacity impairments compared to short- and long-distance walk tests in persons with multiple sclerosis.
Effects of a full-body electrostimulation garment application in a cohort of subjects with cerebral palsy, multiple sclerosis, and stroke on upper motor neuron syndrome symptoms.
Personalised inpatient multidisciplinary rehabilitation elicits clinically relevant improvements in physical function in patients with multiple sclerosis - The Danish MS Hospitals Rehabilitation Study.