Actively Recruiting
Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients
Led by Istituto Ortopedico Rizzoli · Updated on 2025-07-04
30
Participants Needed
1
Research Sites
151 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study consists of 3 phases (enrollment, infiltrative procedure, and controls): * Identification by specialized orthopedic medical staff belonging to the SC Orthopedic and Trauma Clinic II of the Rizzoli Orthopedic Institute of subjects who meet the study inclusion criteria. Signing of informed consent form and completion of evaluation questionnaires. * infiltrative procedure * Patients will be clinically evaluated before the infiltration procedure and at 1, 3, 6, and 12 months after treatment by trained medical personnel (outcome assessors). Questionnaires will be administered for clinical evaluations before treatment and at these clinical checkups during follow-up. Any adverse events to treatment will also be assessed during follow-up visits. The duration and extent of joint swelling and pain following infiltration will be reported, and any drug therapies taken by the patient will be recorded.
CONDITIONS
Official Title
Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patients aged 18 to 40 years
- Symptomatic knee osteoarthritis with unilateral involvement
- Radiographic or MRI evidence of knee cartilage degeneration (Kellgren-Lawrence grade 1-3)
- Ability and consent to actively participate in clinical follow-up
- Signed informed consent form
- Knee pain score of 4 or higher on the visual analog scale (VAS)
You will not qualify if you...
- Unable to provide informed consent
- Received intra-articular knee injections of other substances in the previous 6 months
- Underwent knee surgery in the previous 12 months
- Diagnosed with malignant tumors
- Presence of rheumatic diseases
- Uncontrolled metabolic diseases
- Hematological diseases such as coagulopathies
- Abuse of alcohol, drugs, or medications
- Knee trauma treated within the past 6 months
- Other conditions that could interfere with the evaluation of osteoarthritis treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS - Istituto ortopedico Rizzoli
Bologna, Italy, 40136
Actively Recruiting
Research Team
M
Mirco Lo Presti, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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