Actively Recruiting
HONEY for the Treatment of POst-Tonsillectomy Pain
Led by East and North Hertfordshire NHS Trust · Updated on 2025-04-29
100
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
Sponsors
E
East and North Hertfordshire NHS Trust
Lead Sponsor
M
Manuka Doctor UK Ltd
Collaborating Sponsor
AI-Summary
What this Trial Is About
Double-blind, randomised, placebo controlled, single-site trial in adults to compare the effect of Manuka honey with standard of care compared to placebo with standard of care on post-tonsillectomy pain and postoperative outcomes. Main aim is to investigate a potential improvement in post-tonsillectomy pain control, with a low cost and freely available alternative to conventional analgesics. Recent systematic review and multidisciplinary consensus suggest a potential role for the inclusion of honey for this purpose. Clinical efficacy over placebo remains to be conclusively demonstrated in robust clinical trials.
CONDITIONS
Official Title
HONEY for the Treatment of POst-Tonsillectomy Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult (18 years old or older at the time of giving consent)
- Consented and listed for bilateral tonsillectomy or adenotonsillectomy
- Tonsillectomy performed within the trial study period
You will not qualify if you...
- Any concurrent head and neck malignancy
- Unilateral tonsillectomy
- Pregnancy
- Concurrent pharyngeal or upper aerodigestive tract biopsy
- Robotic tonsillectomy
- Previous head and neck malignancy
- Previous head and neck radiotherapy
- Type 1 or type 2 diabetes mellitus
- Known allergy to bee related products
- Known allergy to golden syrup
- History of chronic pain
- History of fibromyalgia
- Current use of chronic analgesia (more than 6 weeks)
- High-risk anaesthetic patients
- Children or adolescents under 18 years old
- Adults unable to consent for themselves
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Lister Hospital
Stevenage, United Kingdom, SG1 4AB
Actively Recruiting
Research Team
C
Carina Cruz
CONTACT
T
Toral Odedra
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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