Actively Recruiting
The HOPE Study: Characterizing Patients With Hepatitis B and C
Led by University of Maryland, Baltimore · Updated on 2025-05-15
550
Participants Needed
2
Research Sites
1043 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is an observational, longitudinal, prospective study for sample collection and evaluation for future therapy or disease progression of chronic hepatitis B and C. Participants will be seen on an annual basis with optional additional visits for up to 10 years and provide samples for research and evaluation of disease progression. In addition, there is a longitudinal sub-study for treatment of hepatitis B that will involve 2 years of treatment with tenofovir alafenamide and blood collections with optional liver biopsies.
CONDITIONS
Official Title
The HOPE Study: Characterizing Patients With Hepatitis B and C
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 18 years old
- Infected with hepatitis B and/or C, or have a history of hepatitis B infection but cleared, or have been successfully treated for hepatitis C with direct acting antiviral agents, with or without HIV infection, or be a healthy volunteer without a history of hepatitis B, hepatitis C, or HIV
- Willing to have samples stored for future research
- Must have an identifiable primary care provider or be in the process of establishing one
- Willing to undergo HIV testing if not recently documented
- Eligibility for the hepatitis B treatment sub-study depends on meeting criteria for nucleos(t)ide analogue therapy according to standard care
You will not qualify if you...
- Unable to comply with research study visits
- Poor venous access preventing laboratory collection
- Any condition the investigator considers a contraindication to study participation
- For hepatitis B monoinfected participants, any contraindications to nucleos(t)ide analogue treatment excludes participation in the hepatitis B treatment sub-study
- Pregnant or breastfeeding women are not eligible for the hepatitis B treatment sub-study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Institute of Human Virology, University of Maryland School of Medicine
Baltimore, Maryland, United States, 21201
Actively Recruiting
2
Dr Huong Dang, Medical Practice
Falls Church, Virginia, United States, 22044
Actively Recruiting
Research Team
L
Lydia Tang, MBChB
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here