Actively Recruiting

Age: 0 - 90Years
All Genders
Healthy Volunteers
NCT01884051

Hormonal, Metabolic, and Signaling Interactions in PAH

Led by Vanderbilt University Medical Center · Updated on 2025-09-16

1899

Participants Needed

1

Research Sites

1034 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Our hypothesis is that optimal treatment of the dysfunctional metabolic pathways which underlie PAH will improve pulmonary vascular function and consequences of the disease.

CONDITIONS

Official Title

Hormonal, Metabolic, and Signaling Interactions in PAH

Who Can Participate

Age: 0 - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of idiopathic, heritable, or associated pulmonary arterial hypertension, or family member of affected persons
  • Age 0 to 90 years (age 12 to 90 years for skin biopsy in Project 1)
  • Reasonable access to clinic for blood collection and testing (Project 2)
  • Ability to tolerate fasting before sample collection and endothelial function testing (Project 2)
  • Age 7 to 90 years for Project 3
Not Eligible

You will not qualify if you...

  • Diagnosis other than idiopathic, heritable, or associated pulmonary arterial hypertension
  • Age greater than 90 years
  • Age less than 12 years or greater than 90 years for skin biopsy in Project 1
  • Difficulty accessing clinic for blood collection and testing (Project 2)
  • Unable to tolerate fasting state (Project 2)
  • Age less than 7 years or greater than 90 years for Project 3

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Vanderbilt University Medical Center

Nashville, Tennessee, United States, 37232

Actively Recruiting

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Research Team

K

Kelly L Fox

CONTACT

S

Shannon Cordell, BSN

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Hormonal, Metabolic, and Signaling Interactions in PAH | DecenTrialz