Educational Support for Hormone Replacement Therapy Decisions After Risk-Reducing Salpingo-oophorectomy in Women with BRCA1 or BRCA2 Mutations A Pilot Randomized Trial

What this Trial Is About

This research aims to develop an educational tool about hormone replacement therapy HRT to help patients with BRCA1 or BRCA2 mutations make informed decisions before undergoing risk-reducing salpingo-oophorectomy RRSO. The study is a pilot randomized trial involving individuals from gynecologic oncology and high-risk breast clinics who are planning to have RRSO. The goal is to improve counseling and decision-making regarding HRT in this specific group. Participants will be randomly assigned to one of two groups the control group receives usual provider counseling and standardized written education about postoperative HRT, while the experimental group receives the same counseling and written materials plus a video-based educational aid explaining the risks and benefits of HRT. This setup will help researchers compare the impact of standard education alone versus education supplemented with video. During the study, participants levels of decisional conflict before and after the intervention, their satisfaction with counseling and decisions, and their postoperative choices regarding HRT use will be measured. Follow-up assessments occur up to six months post-surgery. This study will gather pilot data to support a larger trial and aims to enhance informed decision-making for women with BRCA mutations considering HRT after RRSO.

Hormone Replacement Therapy After Risk Reducing Salpingo-oophorectomy