Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06132451

In-Hospital Detection of Elevated Blood Pressure: Prevalence of New or Uncontrolled Hypertension and Safety of Delaying Treatment Changes in Medical In-patients

Led by Annina Vischer · Updated on 2024-09-19

800

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial studies the occurrence of new or uncontrolled high blood pressure (hypertension) after hospital discharge in patients who had elevated blood pressure during their stay in a medical ward. It aims to find out if high blood pressure measured in the hospital reflects a real ongoing condition after discharge and whether it is safe to delay changes in blood pressure treatment until after discharge and proper evaluation. Participants are randomly assigned to one of two groups: one group receives treatment based on their physician's decision during hospitalization, while the other group postpones any changes to their blood pressure medication until after a 24-hour ambulatory blood pressure measurement taken 4 weeks after leaving the hospital. This approach allows comparison between usual care and delayed treatment adjustment. During the study, participants will have blood pressure measured at baseline and will be monitored for complications related to high or low blood pressure up to 4 weeks after discharge. Researchers will assess the prevalence of ongoing hypertension, hospital readmissions, and safety of postponing treatment changes. The total monitoring period covers the hospitalization and the four weeks following discharge.

CONDITIONS

Brief Title

In-Hospital Detection of Elevated Blood Pressure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient hospitalized on the internal medicine ward for non-cardiovascular causes
  • Asymptomatic elevated blood pressure readings (140-180 mmHg systolic and/or 90-110 mmHg diastolic) on at least two occasions
  • Ability to understand study procedures and provide written informed consent
Not Eligible

You will not qualify if you...

  • Hospitalization for conditions worsened by uncontrolled hypertension, including cerebrovascular events, acute coronary syndrome, or acute/decompensated heart failure
  • Any condition preventing ambulatory blood pressure monitoring
  • Pregnant or lactating women
  • Failure to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit (in-person)

Diagnostic Evaluation

Duration - 4 weeks after hospital discharge

Participants undergo blood pressure measurements and ambulatory blood pressure monitoring after hospital discharge to assess hypertension status.

1 visit at baseline and 1 ambulatory blood pressure monitoring session 4 weeks after hospital discharge

Long-term Monitoring

Duration - Until 4 weeks after hospital discharge

Participants are observed for hypertensive and hypotensive complications and re-hospitalization up to 4 weeks after hospital discharge.

Follow-up contacts as needed during 4 weeks post-discharge

Trial Site Locations

Total: 1 location

1

University Hospital Basel

Basel, Switzerland, 4031

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Research Team

A

Annina Vischer, M.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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