Noninvasive estimation of right atrial pressure from the inspiratory collapse of the inferior vena cava.
B J Kircher, R B Himelman, N B Schiller
https://pubmed.ncbi.nlm.nih.gov/2386120/Actively Recruiting
Led by Flevoziekenhuis · Updated on 2024-10-23
150
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating the use of point-of-care ultrasound POCUS of the inferior vena cava IVC to assess volume status in hospitalized adults. This study focuses on patients admitted to general wards for at least 24 hours who have a clinical need for an IVC ultrasound. The goal is to understand how well this ultrasound method, performed by trained ward physicians using a standardized technique, can help identify whether patients are hypovolemic or hypervolemic in a non-critical care setting. The study involves performing ultrasound scans of the IVC at the bedside using a point-of-care device. Physicians capture 10-second cine loops during respiratory cycles to measure the IVC diameter at specific points. Data collection occurs at admission and again after 48 hours or earlier if discharged. The study collects patient demographics, clinical exams, vital signs, lab results, and ultrasound measurements, alongside scoring health status and comorbidities. The influence of POCUS on treatment decisions such as fluid or diuretic therapy is also recorded. Participants will undergo initial and follow-up assessments including physical exams, vitals, lab tests, and ultrasound imaging. The study analyzes diagnostic accuracy for volume status, including sensitivity and specificity, and evaluates the quality of ultrasound images. Follow-up measurements allow analysis of changes over time. The primary outcome is volume status at 48 hours. Data will help determine the best measurement locations and cutoff values for clinical use of IVC ultrasound in this patient group.
CONDITIONS
HOspitalized Patients and Clinical flUid Status, Assessment Using Point Of Care UltraSound
K
Koen de Heer, MD PhD
D
Didier Collard, MD PhD
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Flevoziekenhuis
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for initial assessment and consent
Duration - At admission and 48 hours after (or earlier if discharged)
Participants undergo point-of-care ultrasound to assess their volume status and other clinical data are collected.
2 visits (in-person) occurring at admission and 48 hours later
Duration - Up to 48 hours after initial evaluation
Participants' clinical status and volume status are observed through follow-up data collection to evaluate changes over time.
1 follow-up visit (in-person) approximately 48 hours after initial ultrasound
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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B J Kircher, R B Himelman, N B Schiller
https://pubmed.ncbi.nlm.nih.gov/2386120/Flevoziekenhuis
Lead Sponsor