Actively Recruiting
A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families
Led by University College Cork · Updated on 2026-03-18
390
Participants Needed
2
Research Sites
19 weeks
Total Duration
On this page
Sponsors
U
University College Cork
Lead Sponsor
U
University College Dublin
Collaborating Sponsor
AI-Summary
What this Trial Is About
Vitamin D deficiency is common. It is caused by limited sun availability together with a low supply of vitamin D in the food system. There is a high prevalence of low vitamin D status around the world. In Ireland, our relatively northern latitude and prevailing weather mean that UVB availability for skin synthesis of vitamin D is limited in this country and our population relies on the dietary supply of vitamin D to prevent deficiency. Thus, the endemic Irish problem of vitamin D malnutrition is due to the lack of vitamin D in our food system. Dietary guidelines cannot address this issue because foods naturally rich in vitamin D are very few and infrequently consumed. The FamDBread study will test the hypothesis that a vitamin D-fortified bread as part of a healthy diet that includes vitamin D-fortified foods is effective in preventing low vitamin D status during winter, and safe for families to consume.
CONDITIONS
Official Title
A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Provide written informed consent if over 16 years; parental consent and child assent for those under 16 years
- Household must include at least one adult aged 18 or older and at least one dependent aged 5 years or older
- Willing to consume the provided bread and have freezer space to store frozen bread
- Be in good general health
- Willing to follow the assigned diet for 8 weeks and attend all required appointments
You will not qualify if you...
- Daily intake of vitamin D supplements exceeding 10 micrograms (400 IU)
- Recent exposure to factors affecting vitamin D status, such as winter sun holidays, ski holidays, or tanning beds
- Following a medically prescribed diet
- Diagnosed with medical conditions affecting vitamin D absorption or metabolism, including Coeliac disease, Inflammatory Bowel Disease, cystic fibrosis, liver or kidney disease
- History of active cancer or cancer diagnosis within the past 5 years
- Allergy to bread ingredients
- Participating in another research study or lifestyle program that could affect study outcomes
- Unable to read, write, or understand English
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Human Nutrition Studies Unit, School of Food and Nutritional Sciences
Cork, Co. Cork, Ireland, T12 K8AF
Not Yet Recruiting
2
UCD Institute of Food and Health
Dublin, Ireland
Actively Recruiting
Research Team
M
Maired Kiely, PhD
CONTACT
K
Kevin Cashman, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here