Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
Healthy Volunteers
NCT07191197

How do Patients With Amnesia Acquire New Knowledge?

Led by University Hospital, Toulouse · Updated on 2026-05-08

150

Participants Needed

2

Research Sites

199 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Toulouse

Lead Sponsor

N

National Research Agency, France

Collaborating Sponsor

AI-Summary

What this Trial Is About

THE STUDY AIMS to constitute the largest group of patients with major memory impairment resulting from various etiology and specific lesions of the medial temporal lobe (MTL) and use a combined psychometric and neuroimaging approach to study the factors allowing these patients to successfully learn new semantic information.

CONDITIONS

Official Title

How do Patients With Amnesia Acquire New Knowledge?

Who Can Participate

Age: 18Years - 70Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged between 18 and 70 years
  • Living in France for less than 20 years and able to understand French with basic cultural knowledge
  • Provided written agreement to participate in the study
  • Intellectual abilities sufficient for cognitive tasks and consent
  • Affiliated with the French social security system
  • Have bilateral brain lesion of the medial temporal lobe or extended hippocampal system
Not Eligible

You will not qualify if you...

  • Under 18 years old or over 70 years old
  • Contraindications for MRI such as pacemaker, cardiac defibrillator, activated implants, haemostatic clips, orthopedic implants, or claustrophobia
  • Refusal to be informed of any anomaly detected during MRI

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

University Hospital of Caen

Caen, France

Active, Not Recruiting

2

University Hospital of Toulouse

Toulouse, France

Actively Recruiting

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Research Team

J

Jérémie PARIENTE, MD + PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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