Actively Recruiting
HPV Screening With Triage by HPV Genotyping Versus Visual Inspection With Acetic Acid
Led by Prof. Patrick Petignat · Updated on 2024-05-09
5500
Participants Needed
2
Research Sites
186 weeks
Total Duration
On this page
Sponsors
P
Prof. Patrick Petignat
Lead Sponsor
U
University Hospital, Geneva
Collaborating Sponsor
AI-Summary
What this Trial Is About
Cervical cancer is the leading cause of cancer death among women in sub-Saharan Africa, despite the existence of effective prevention and screening methods. Because vaccination rates against human papillomavirus (causing nearly all cervical cancers) are still insufficient in some low-resource countries, early detection and treatment of cervical lesions at risk of progressing to cancer are crucial components of cervical cancer control. Therefore, it is essential to find the most reliable and appropriate screening strategy in the context of low-resource countries in order to identify women in need of treatment and thus prevent the development of cervical cancer. The objective of our study is to compare two different methods of cervical cancer screening adapted to low-resource settings, in two study centers in Cameroon.
CONDITIONS
Official Title
HPV Screening With Triage by HPV Genotyping Versus Visual Inspection With Acetic Acid
Who Can Participate
Eligibility Criteria
You may qualify if you...
- HIV-negative women aged 30-49 years
- HIV-positive women aged 25-49 years
- Ability to understand study procedures and voluntarily sign informed consent
You will not qualify if you...
- Pregnancy at the time of screening
- Previous hysterectomy
- Known cervical cancer
- Symptoms of cervical cancer such as metrorrhagia or known pelvic mass
- Conditions interfering with visualization of the cervix
- Severe pre-existing medical conditions like advanced cancer or terminal renal failure
- Inability to comply with the study protocol
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Trial Site Locations
Total: 2 locations
1
Dschang Annex Regional Hospital
Dschang, Menoua, Cameroon
Actively Recruiting
2
Bafoussam Regional Hospital
Bafoussam, Mifi, Cameroon
Not Yet Recruiting
Research Team
P
Patrick Petignat, PD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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