Actively Recruiting
Health Related Quality of Life in Thyroid Cancer Patients and Patients With Thyroid Nodules Suspicious of Cancer
Led by Oslo University Hospital · Updated on 2022-03-11
200
Participants Needed
1
Research Sites
261 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the quality of life in patients undergoing thyroid surgery, either for diagnostic reasons or as part of treatment for thyroid cancer. Previous studies in Europe suggest that people with thyroid cancer may experience a lower quality of life compared to the general population, similar to those with other cancers. This research aims to understand whether the diagnosis or the surgery itself has a greater impact on quality of life. Participants will have standard medical care for their thyroid tumors, including planned hemi- or total thyroidectomy. They will be grouped into those with benign tumors, malignant tumors treated with radioiodine, and malignant tumors without radioiodine treatment. Quality of life will be assessed before surgery and at 6 and 12 months afterward using validated questionnaires designed to measure general health-related quality of life, thyroid cancer-specific symptoms, and fatigue. During the study, participants will complete questionnaires at three time points: before surgery, and 6 and 12 months after surgery. Clinical data will be collected from medical records. The main measurement is the change in global health-related quality of life approximately 12 months after surgery. Secondary outcomes include changes in fatigue and quality of life related to radioiodine treatment and tumor type. Those who cannot attend follow-up visits will receive questionnaires by mail. The study will continue until April 2028.
CONDITIONS
Brief Title
HRQOL in Thyroid Cancer and Thyroid Tumours
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Planned hemi- or total thyroidectomy at the ENT Department of Oslo University Hospital
- Thyroid tumor with fine needle aspiration results of Bethesda 3-6 or other clinical signs suspicious of cancer
- Ability to understand and complete questionnaires
- Provided informed consent to participate
You will not qualify if you...
- Unable to complete or understand the questionnaires
- Age below 18 years
- Thyroid surgery within the last 2 years
- Thyroid surgery for reasons other than listed in inclusion criteria
- Participants who have had postoperative external radiotherapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to surgery date
Participants undergo standard clinical evaluation and diagnostic surgery for thyroid tumors.
1 visit for surgery
Duration - 12 months after surgery
Participants complete questionnaires on health-related quality of life before surgery and at follow-up visits after surgery to assess recovery and treatment impact.
1 baseline visit and 2 follow-up visits at 6 and 12 months; questionnaires may be completed by mail if participants do not attend follow-up visits
Trial Site Locations
Total: 1 location
1
ENT department, Oslo University Hospital
Oslo, Norway
Actively Recruiting
Research Team
B
Bianca MR Lorntzsen, MD
T
Terje A Osnes, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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