Actively Recruiting
HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors
Led by Shanghai Hengrui Pharmaceutical Co., Ltd. · Updated on 2026-01-14
60
Participants Needed
1
Research Sites
98 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is a randomized, open-label, multicenter Phase II clinical trial designed to evaluate the Safety, Tolerability and Preliminary Efficacy of HRS-4642 Combination with Other Antitumor Therapies in Patients with Solid Tumors
CONDITIONS
Official Title
HRS-4642 Combination With Other Antitumor Therapies in Patients With Solid Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years old, any gender
- ECOG performance status of 0 or 1
- Life expectancy of at least 12 weeks
- Diagnosed with unresectable locally advanced or metastatic pancreatic cancer
- Pancreatic duct adenocarcinoma confirmed by histopathology
- Provide tumor tissue samples obtained within 3 years before starting treatment
- Have at least one measurable tumor lesion according to RECIST 1.1 criteria
You will not qualify if you...
- Untreated or active central nervous system tumor metastasis
- Not recovered from previous treatment side effects or complications to the required safety levels
- Known or suspected interstitial pneumonia
- Grade 3 or higher serous fluid buildup or large abdominal fluid accumulation needing recent drainage
- Acute or chronic pancreatitis with significant clinical symptoms
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China, 100730
Actively Recruiting
Research Team
Z
Zengquan Gu
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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