Actively Recruiting
HTA of NIVATS Based on RWE
Led by Fudan University · Updated on 2024-08-27
400
Participants Needed
1
Research Sites
27 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research focuses on a Health Technology Assessment (HTA) of non-intubated video-assisted thoracic surgery (VATS) for lung nodules. Lung cancer, one of the most prevalent malignancies globally, has a high incidence and mortality rate, particularly in China. Traditional treatments like thoracotomy are highly invasive, while conventional thoracoscopic surgery can induce anesthesia-related complications. Non-intubated VATS offers a promising alternative by avoiding intubation and mechanical ventilation, thus reducing complications, anesthesia burden, and recovery time. The study aims to comprehensively assess the clinical effectiveness, safety, and economic viability of non-intubated VATS for lung cancer treatment through systematic literature reviews, real-world evidence (RWE), and cost-effectiveness analysis. The research will also explore patient preferences using discrete choice experiments (DCE). By evaluating this technology from a Chinese perspective, the study seeks to provide evidence-based recommendations for the broader adoption of non-intubated VATS in clinical settings.
CONDITIONS
Official Title
HTA of NIVATS Based on RWE
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with pulmonary nodules or lung cancer and scheduled for minimally invasive lung surgery (wedge resection, segmentectomy, or lobectomy)
- Aged between 18 and 75 years, any gender
- Medically assessed as able to tolerate non-intubated video-assisted thoracic surgery (for experimental group) or minimally invasive surgery (for control group)
- Signed informed consent and voluntarily agrees to participate in the study
You will not qualify if you...
- Unable to provide sufficient preoperative and postoperative follow-up data
- Pregnant or breastfeeding women
- Severe heart or lung dysfunction making surgery unsafe
- Previous surgery or radiotherapy in the same chest area
- Active infections or severe other illnesses that could affect surgery results
- Mental illness or cognitive impairment preventing understanding of the study or compliance with follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
School of Public Health, Fudan University
Shanghai, Shanghai Municipality, China, 200032
Actively Recruiting
Research Team
Y
Yingyao Chen, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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