Actively Recruiting
Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma Following Local Ablation
Led by Yue Han · Updated on 2024-05-31
828
Participants Needed
17
Research Sites
350 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To evaluate the efficacy and safety of Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma following Local Ablation
CONDITIONS
Official Title
Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma Following Local Ablation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years, male or female
- Diagnosed with hepatocarcinoma based on tissue examination or imaging criteria
- Radiographic confirmation of cancer elimination four weeks after local ablation with complete response
- Solitary tumor smaller than 5 cm, or up to 3 tumors with largest under 3 cm
- Hemoglobin ≥90 g/L, platelets ≥60×10⁹/L, absolute neutrophil count >1.0×10⁹/L, prothrombin activity >50%, serum creatinine less than 1.5 times upper limit of normal, total bilirubin <51.3 µmol/L
- ECOG performance status score of 0 to 1
- Liver function classified as Child-Pugh grade A or B
- History of TACE treatment for hepatocarcinoma no more than twice
- Volunteered to participate, signed informed consent, and agree to cooperate with data collection
You will not qualify if you...
- Cancer cells not eliminated after four weeks of local ablation as shown by radiographic testing
- Presence of embolism in large liver blood vessels, extrahepatic metastasis, or liver transplantation
- Receiving or planned chemotherapy or molecular targeted therapy
- Planned to receive TACE treatment for hepatocarcinoma
- No prior treatment with Huaier granules
- History of diabetes
- Uncontrolled or likely to develop ascites, hepatic encephalopathy, or upper gastrointestinal bleeding
- Severe cardiopulmonary insufficiency, renal insufficiency, or severe mental illness
- Other infectious diseases excluding viral hepatitis
- Unable to take oral medication
- Any condition deemed unsuitable for study participation by investigators
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 17 locations
1
The First Affiliated Hospital of Sun Yat-sen University
Guangzhou, Guangdong, China
Actively Recruiting
2
Shijiazhuang Fifth Hospital
Shijiazhuang, Hebei, China
Actively Recruiting
3
Affiliated Cancer Hospital of Harbin Medical University
Harbin, Heilongjiang, China
Actively Recruiting
4
Henan Cancer Hospital
Zhengzhou, Henan, China
Actively Recruiting
5
Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology
Wuhan, Hubei, China
Actively Recruiting
6
The Affiliated Zhongshan Hospital of Dalian University
Dalian, Liaoning, China
Actively Recruiting
7
The Second Hospital of Dalian Medical University
Dalian, Liaoning, China
Actively Recruiting
8
Shandong Provincial Hospital
Jinan, Shandong, China
Actively Recruiting
9
The Second Hospital of Shandong University
Jinan, Shandong, China
Actively Recruiting
10
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China
Actively Recruiting
11
First Affiliated Hospital of Xi'an Jiaotong University
Xi’an, Shanxi, China, 710061
Actively Recruiting
12
the Second Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Actively Recruiting
13
Beijing You 'an Hospital, Capital Medical University
Beijing, China
Actively Recruiting
14
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Beijing, China
Actively Recruiting
15
Chinese PLA General Hospital
Beijing, China
Suspended
16
Chongqing Cancer Hospital
Chongqing, China
Actively Recruiting
17
Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Shanghai, China
Actively Recruiting
Research Team
Y
Yue Han, Professor
CONTACT
H
Han
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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