Actively Recruiting
Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2026-04-24
10000
Participants Needed
1
Research Sites
1809 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Background: Studies show that rare genetic variants might lead to diseases. Researchers want to collect blood and tissue samples so they can study them and better understand diseases. Objective: To collect blood and tissue samples for studies to identify underlying causes of disease. Eligibility: People of all ages Design: Participants will have blood and/or tissue samples collected. Samples can be collected at the NIH Clinical Center. Participants doctors can collect the samples and send them to NIH. NIH staff can collect samples off site. For blood samples, blood is taken from an arm vein using a needle. Tissue collection may involve: Buccal smear: Cells are collected by scraping the inside of the cheek with a cotton swab. Saliva collection: Participants spit into a cup. Skin biopsy: A special needle takes a very small skin sample. Surgical waste tissue: If participants have surgery, NIH may receive samples of tissue that would routinely be removed. Umbilical cord or cord blood collection: If a participant has a baby, NIH may receive a small piece of the umbilical cord or blood from the cord once the baby is delivered.
CONDITIONS
Official Title
Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age older than 1 month
- Pregnant women affected with known or suspected pathology
- Unaffected related pregnant women (including spouses/partners) for cord blood and tissue collection at delivery only
- Cognitively impaired individuals who are affected
- Cognitively impaired individuals related to an affected subject
- Willingness to provide informed consent
You will not qualify if you...
- Healthy volunteers unable to give informed consent
- Cognitively impaired individuals who are not affected
- Cognitively impaired individuals not related to affected subjects
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
W
William R Whalen, C.R.N.P.
CONTACT
M
Manfred Boehm, M.D.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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