Actively Recruiting
Human Clinical Trial Evaluating the Blood Glucose-Regulating Effects of Momordica Charantia Peptides
Led by Chung Shan Medical University · Updated on 2026-03-31
12
Participants Needed
1
Research Sites
20 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prediabetes is a metabolic condition characterized by elevated blood glucose levels that are higher than normal but below the diagnostic threshold for diabetes. Early intervention to improve glycemic control may help delay the progression to type 2 diabetes. Momordica charantia (bitter melon) peptides have been reported to possess potential glucose-regulating effects. This study aims to evaluate the effects of BmpP® bitter melon peptide supplementation on glycemic control in adults with prediabetes. This study is designed as a 12-week single-arm, open-label clinical trial. Approximately 12 adults aged 30-65 years with prediabetes will be recruited. Participants will consume bitter melon peptide capsules three times daily before meals for 12 weeks. Primary outcomes include fasting blood glucose, postprandial glucose response, and HbA1c levels. The findings of this study may provide preliminary evidence regarding the potential role of bitter melon peptides in blood glucose regulation.
CONDITIONS
Official Title
Human Clinical Trial Evaluating the Blood Glucose-Regulating Effects of Momordica Charantia Peptides
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 30 to 65 years, male or female
- Prediabetes defined by any of the following: fasting blood glucose 100-125 mg/dL, HbA1c 5.7-6.4%, or 2-hour OGTT glucose 140-199 mg/dL
- Body mass index between 24 and 35 kg/m² with waist circumference recorded (men 60 cm; women 60 cm)
- Stable lifestyle including diet, physical activity, and sleep habits for the past three months
- No use of blood glucose-regulating supplements before or during the study
- Willing to comply with study procedures and complete assessments
- Provided written informed consent
You will not qualify if you...
- Diagnosis of type 2 diabetes mellitus (HbA1c 6.5% or physician diagnosis)
- Current use of antidiabetic medications like metformin or insulin
- Use of medications affecting blood glucose such as corticosteroids or antipsychotics
- Severe liver, kidney, heart disease, active cancer, or gastrointestinal malabsorption
- Pregnant, breastfeeding, or planning pregnancy
- Body weight change over 7% in past three months or on weight-loss diet
- History of alcohol abuse or substance misuse
- Working night or rotating shifts
- Allergy to any study product component
- Participation in another clinical trial within past month or antibiotic use within 8 weeks
- Being a student, staff, or employee related to the investigators
AI-Screening
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Trial Site Locations
Total: 1 location
1
Chung Shan Medical University
Taichung, Taiwan
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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