Actively Recruiting
Human Intracranial Electrophysiology
Led by Dartmouth-Hitchcock Medical Center · Updated on 2026-01-15
175
Participants Needed
1
Research Sites
497 weeks
Total Duration
On this page
Sponsors
D
Dartmouth-Hitchcock Medical Center
Lead Sponsor
D
Dartmouth College
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will enroll patients with epilepsy who are being evaluated for epilepsy surgery and have electrodes implanted in the brain and/or have electrodes on the scalp. Additionally, this study will recruit normal and online controls (participants who do not have epilepsy). Participants will be asked to participate in 1 to 2 (30-90 minutes) daily sessions designed to test aspects of human cognition such as memory, speech, language, feeling, movement, attention, sound perception, and emotions. Generally, this will involve working on a computer, looking at pictures or watching videos, and answering questions. Additionally, participants may be asked to be hooked up to additional equipment such as eye tracker, electrical stimulator, heart rate monitor, sweat monitor or other non-invasive equipment. The overall aim of this study is to use human intracranial electrophysiology (the recording of the electrical activity of the human brain) to study localization and function of the human brain.
CONDITIONS
Official Title
Human Intracranial Electrophysiology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Must be 18 years or older with no upper age limit
- Patients with intracranial EEG must have refractory epilepsy and be undergoing intracranial EEG recording for clinical reasons
- Patients with scalp EEG must have a probable diagnosis of epilepsy
- Normal control participants must be able to provide informed consent for themselves
You will not qualify if you...
- Having additional neurological conditions such as stroke or dementia
- Having psychiatric conditions like active psychosis or suicidal thoughts that make participation inappropriate
- Unable to provide informed consent due to reasons like being encephalopathic or currently experiencing a seizure
- Normal controls deemed not appropriate for the study population
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03776
Actively Recruiting
Research Team
K
Krzysztof A Bujarski, MD
CONTACT
G
Gina Kersey
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
4
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