Actively Recruiting
Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas
Led by Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · Updated on 2024-12-31
550
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Head and neck squamous cell carcinoma (HNSCC) represents a significant public health burden in Bangladesh with a high incidence and mortality rate. While traditional risk factors like tobacco and betel nut chewing contribute to HNSCC incidence, the emergence of HPV-associated HNSCC presents a unique challenge. The main goal of this observational study is to explore the prevalence, risk factors, and biological mechanisms underlying food habits and HPV-driven HNSCC in the population and identify the genomic changes and characteristics related to this malignancy. This study will provide the prevalence of HPV-associated HNSCC and screening the HPV typing in the Bangladeshi population, identify risk factors, and any biologically driven mechanisms causing HNSCC.
CONDITIONS
Official Title
Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell Carcinomas
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient is an adult aged over 18 years
- Diagnosed with head and neck squamous cell carcinoma confirmed by biopsy
- Cancer located in specific head and neck areas: oral cavity, oropharynx, hypopharynx, larynx, or tongue
- Patient provides consent to participate
You will not qualify if you...
- Patient is younger than 18 years
- Cancer present in any part of the body other than the head and neck region
- No diagnosis of head and neck squamous cell carcinoma
- Presence of chronic diseases, genetic disorders, or acute/chronic infectious diseases
AI-Screening
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Trial Site Locations
Total: 1 location
1
Bangabandhu Sheikh Mujib Medical University (BSMMU)
Dhaka, Dhaka Division, Bangladesh, 1000
Actively Recruiting
Research Team
S
S M Rashed Ul Islam, M. Phil, MPH
CONTACT
S
Syed Farhan Ali Razib, FCPS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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