Actively Recruiting
Human Umbilical Cord Mesenchymal Stem Cells Treatment in Sepsis
Led by Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Updated on 2025-05-25
180
Participants Needed
1
Research Sites
136 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective: To evaluate the efficacy of intravenous infusion of universal UC-MSCs and CD83+MSCs subpopulation injection in the treatment of sepsis by using the 28-day survival rate of the subjects as the primary efficacy criterion.The secondary objectives: 1. To systematically evaluate the safety of universal UC-MSCs and CD83+MSCs subpopulation in the treatment of sepsis; 2. To provide theoretical basis and clinical research data for establishing a safe, effective and feasible clinical treatment plan for sepsis using stem cells.
CONDITIONS
Official Title
Human Umbilical Cord Mesenchymal Stem Cells Treatment in Sepsis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 0 to 65 years old with a diagnosis of sepsis
- Clinical diagnosis of sepsis based on Sepsis 3.0 International Guidelines
- Confirmed or suspected infection
You will not qualify if you...
- Violation of medical ethics
- Significant factors that may bias study results
- Poor adherence to study protocol
- Participation in other clinical trials
- History of chronic enteritis, neuropsychiatric disorders, or organ transplantation (bone marrow, lung, liver, pancreas, or small intestine)
- Severe primary diseases affecting survival or psychiatric disorders
- History of hypersensitivity or severe adverse reactions to biological products
- Imminent terminal status with life expectancy under 7 days
- Risk of medical errors or disputes during hospitalization
- Active drug-resistant infections
- History of malignancy at screening
- Pregnancy, lactation, or plans for pregnancy within the next year
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Chongqing, Chongqing Municipality, China, 400010
Actively Recruiting
Research Team
X
Xiang Xu, Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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