Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT07033572

Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma

Led by Fujian Medical University · Updated on 2025-07-03

60

Participants Needed

1

Research Sites

526 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study evaluates a thyroid-function-preserving alternative to routine total thyroidectomy for bilateral papillary thyroid carcinoma (PTC). Eligible adults undergo remote-access gas-less axillo-breast endoscopic hemithyroidectomy with level VI dissection on the dominant side, followed by ultrasound-guided radiofrequency ablation (RFA) of a ≤7 mm contralateral focus during the same anesthesia. Outcomes include structural-recurrence-free survival, endocrine-function preservation, safety, and quality of life over 24 months.

CONDITIONS

Official Title

Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-65 years.
  • Dominant-side papillary thyroid carcinoma 1.5 cm or smaller suitable for endoscopic resection.
  • Contralateral thyroid nodule 7 mm or smaller located at least 2 mm from the posterior capsule.
  • No radiologic evidence of lymph-node metastasis on the contralateral side.
  • Written informed consent provided.
Not Eligible

You will not qualify if you...

  • Extrathyroidal extension or visible nodal or distant metastasis.
  • Previous neck surgery, prior radiofrequency ablation or ethanol injection, or neck irradiation.
  • Pregnancy or breastfeeding.
  • Serious medical conditions preventing anesthesia or follow-up.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fujian Medical University Union Hospital

Fuzhou, Fujian, China, 350001

Actively Recruiting

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Research Team

B

Bo Wang Professor, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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