Actively Recruiting

Phase 1
Phase 2
Age: 18Years - 85Years
All Genders
NCT04550728

Hybrid Robot+FES Stroke Rehabilitation

Led by University of Maryland, Baltimore · Updated on 2025-12-18

60

Participants Needed

1

Research Sites

282 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The investigators have developed a novel robot-guided stretching under intelligent control and combine it with active movement training, which helped increase joint ROM, reduce spasticity and joint stiffness, increase muscle force output, and improve locomotion. However, for stroke survivors with sensorimotor impairment, their peripheral muscle may not sufficiently be recruited. Functional electrical stimulation (FES), has been shown its advantage to activate the peripheral muscles for people with neurological conditions. The investigators thus make a hybrid robot-FES rehabilitation system, combining the advantage of robot and FES technologies for stroke motor recovery. The investigators further would like to translate the technologies from lab to home-based training. Thus, the investigators will conduct a randomized, controlled, primarily home-based clinical trial using an ankle robot alone or combined with functional electrical stimulation (FES) to treat sensorimotor and locomotion impairments post-stroke.

CONDITIONS

Official Title

Hybrid Robot+FES Stroke Rehabilitation

Who Can Participate

Age: 18Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-85
  • Able to walk at least 10 meters without human assistance, with or without an assistive device
  • At least 6 months post stroke
  • Have a caregiver to assist with training at home
Not Eligible

You will not qualify if you...

  • Having expressive and receptive aphasia
  • Unable to follow multi-step commands
  • Currently enrolled in another lower limb rehabilitation program
  • Severe pain in the paralyzed lower limb
  • Ankle plantar flexion contracture greater than 30 degrees
  • Having implanted electronic devices such as a pacemaker, spinal cord stimulator, or deep brain stimulator because FES may interfere with their functions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Maryland School of Medicine

Baltimore, Maryland, United States, 21201

Actively Recruiting

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Research Team

L

Li-qun Zhang, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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