Actively Recruiting
Hybrid Type-1 Effectiveness-Implementation Trial of Motivation Matters! A Theory-Based mHealth Intervention to Support Early Antiretroviral Adherence in HIV+ African Women Who Engage in Sex Work
Led by University of Washington · Updated on 2026-05-12
350
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Washington
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to determine if an interactive mobile health (mHealth) intervention called Motivation Matters! (MM!) can help HIV-positive women who are starting antiretroviral therapy (ART) take their medication regularly and reduce their viral load. The study focuses on women in high-burden settings, comparing the effectiveness of MM! plus standard care versus standard care alone in achieving undetectable HIV viral load by six months. Participants are randomly assigned to one of two groups. The MM! group receives standard care plus personalized, interactive text messages—three messages weekly during the first month, then two messages weekly for the following five months. These messages are tailored based on individual preferences such as name, language, religion, and parental status, and participants reply briefly to each message. The control group receives standard care following Kenyan guidelines, including clinic-based ART adherence education and counseling. During the six-month study period, participants will receive ART and counseling, with regular monitoring of their viral load to assess treatment effectiveness. Researchers will measure the number of women who achieve an undetectable viral load at six months. Adherence is supported and tracked through the interactive messaging in the intervention group, while all participants receive standard counseling and care. The total participation duration is six months from enrollment.
CONDITIONS
Brief Title
Hybrid Type-1 Effectiveness-Implementation Trial of Motivation Matters!
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age >18
- Engaged in transactional sex in the past 12 months
- HIV-positive
- Not currently on antiretroviral therapy
- Enrolled in one of the Sex Workers Outreach Program clinics
- Has access to a mobile phone
- Willing to receive study text messages
- Able to read or have someone else read messages
You will not qualify if you...
- Plans to move away in the next 6 months
- Undetectable viral load at baseline
- Pregnant
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 months
Participants receive either the MM! text message intervention plus standard care or standard care alone to support early antiretroviral adherence.
Weekly text message interactions and periodic clinic visits as part of standard care
Trial Site Locations
Total: 1 location
1
Partner for Health and Development in Africa
Nairobi, Kenya
Actively Recruiting
Research Team
K
Kerri Sloan
R
Raymond S McClelland, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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