Actively Recruiting

Age: 18Years - 99Years
All Genders
NCT06342635

Hydra Single-centre Experience - Copenhagen, Denmark

Led by Sahajanand Medical Technologies Limited · Updated on 2026-04-27

50

Participants Needed

1

Research Sites

175 weeks

Total Duration

On this page

Sponsors

S

Sahajanand Medical Technologies Limited

Lead Sponsor

Q

Qmed Consulting A/S

Collaborating Sponsor

AI-Summary

What this Trial Is About

The present study aims to evaluate the efficacy and safety of TAVI using the Hydra transcatheter aortic valve (THV) series, in patients with severe aortic stenosis up to 1-year after the procedure. Additionally, the study will assess the role of geometry in the development of new conduction abnormalities based on the analysis of post-operative CT scan at 1-month in patients who had undergone transcatheter aortic valve replacement with a self-expanding Hydra THV series.

CONDITIONS

Official Title

Hydra Single-centre Experience - Copenhagen, Denmark

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of severe aortic stenosis with NYHA class II or higher
  • Eligible for TAVI procedure based on local Heart Team evaluation
  • Able to fully understand and willing to provide informed consent for study participation
Not Eligible

You will not qualify if you...

  • Contraindications to TAVI such as specific anatomical phenotypes, intracardiac mass, thrombus, vegetation, or endocarditis
  • Refusal to provide informed consent for study participation
  • Severe aorta or peripheral artery disease preventing transfemoral TAVI approach
  • Presence of calcification on the annulus or left ventricular outflow tract, excess calcium on valve cusps, or deemed unsuitable for the Hydra THV device by the Investigator's clinical judgment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Copenhagen University Hospital, Rigshospitalet

Copenhagen, Denmark

Actively Recruiting

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Research Team

D

Dr. Ole De Backer

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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