Actively Recruiting
Hydroxychloroquine Sulfate Tablets for Radiation-induced Oral Mucositis
Led by Xingchen Peng · Updated on 2025-04-29
158
Participants Needed
1
Research Sites
25 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Evaluate the safety, tolerance and efficacy of hydroxychloroquine sulfate tablets the prevention and treatment of oral mucositis and dysgeusia in patients undergoing radiotherapy
CONDITIONS
Official Title
Hydroxychloroquine Sulfate Tablets for Radiation-induced Oral Mucositis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients pathologically diagnosed with non-metastatic head and neck malignant tumors
- Aged 18-80 years
- Eastern Cooperative Oncology Group performance status of 2
- Planning to receive definitive radiotherapy or postoperative adjuvant radiotherapy
- Normal liver, kidney and bone marrow function
- Signed informed consent
You will not qualify if you...
- Known allergy to 4-aminoquinoline compounds or severe allergic constitution
- History of head and neck radiotherapy
- Radiotherapy area not involving head and neck
- Poor oral hygiene or severe periodontitis
- Severe kidney disease, severe cardiovascular disease, myasthenia gravis, Parkinson's disease or epilepsy
- Recently taking or currently taking diuretics or drugs that interact with hydroxychloroquine sulfate tablets
- Retinopathy
- Other serious diseases deemed unsuitable by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Radiation Oncology
Chengdu, Sichuan, China, 610000
Actively Recruiting
Research Team
P
Peng xingchen Professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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