Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06619808

Hyperbaric Oxygen Therapy for Metabolic Dysfunction-associated Steatotic Liver Diseases

Led by Jinling Hospital, China · Updated on 2024-10-01

150

Participants Needed

1

Research Sites

109 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if hyperbaric oxygen therapy (HBOT) works to treat Metabolic Dysfunction-associated Steatotic Liver Diseases (MASLD). The main questions it aims to answer are: Does HBOT decreases the fat content and fibrosis state of liver in adult MASLD patients? Does HBOT improves the liver function and metabolic condition in adult MASLD patients? Participants will: Receive HBOT for 20 times in 1 month or recerive regular drug; Visit the clinic for checkups and tests at the starting, ending of the therapy and 6 month after the therapy.

CONDITIONS

Official Title

Hyperbaric Oxygen Therapy for Metabolic Dysfunction-associated Steatotic Liver Diseases

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Metabolic dysfunction-associated steatotic liver disease patients
Not Eligible

You will not qualify if you...

  • Unfit for hyperbaric treatment
  • Received oxygen therapy within the last 6 months
  • History of viral hepatitis, hemochromatosis, Wilson disease, autoimmune hepatitis, primary biliary cirrhosis, sclerosing cholangitis, biliary obstruction, or alpha-1 antitrypsin deficiency
  • Severe organ dysfunctions or malignant tumors
  • Weight loss plan or major surgery within the last 6 months
  • Unable to provide informed consent or participating in another clinical trial within the last 3 months
  • Pregnant or lactating
  • Claustrophobia or inability to decompress properly

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

General Hospital of Eastern Theater Command

Nanjing, Jiangsu, China, 210000

Actively Recruiting

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Research Team

L

Lu Chen, MS

CONTACT

M

Miaofang Yang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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