Actively Recruiting
Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome
Led by Assaf-Harofeh Medical Center · Updated on 2026-04-21
91
Participants Needed
1
Research Sites
239 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Post-COVID-19 syndrome is an assembly of symptoms, following an infection with Coronavirus disease 2019 (COVID-19). The syndrome is characterized by cognitive impairment, fatigue, sleep disorders, smell and taste disorders, pain and more. This long-term sequela can last for months after recovering from the virus, and no treatment is known to date. The aim of this study is to compare the effect of HBOT vs. Sham on post COVID-19 syndrome
CONDITIONS
Official Title
Hyperbaric Oxygen Therapy for Post-COVID-19 Syndrome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age above 18 years
- Post-COVID-19 cognitive decline affecting quality of life lasting at least 3 months after confirmed infection
- Willing and able to read, understand, and sign informed consent
You will not qualify if you...
- Unable to attend clinic visits or follow study protocol
- History of traumatic brain injury or other non-COVID brain disorders
- Active cancer
- Substance use at baseline
- Severe or unstable physical illnesses or major cognitive deficits at baseline
- Previous hyperbaric oxygen therapy before enrollment
- Chest conditions incompatible with pressure changes (including moderate to severe asthma)
- Ear or sinus conditions incompatible with pressure changes
- Unable to perform awake brain MRI
- Active smoking
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Assaf-Harofeh medical center
Ẕerifin, Israel, 70300
Actively Recruiting
Research Team
S
Shani Zilberman-Itskovich, Dr.
CONTACT
S
Shai Efrati, Prof.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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