Actively Recruiting
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
Led by Mario Castro, MD, MPH · Updated on 2026-05-06
260
Participants Needed
1
Research Sites
416 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to develop and evaluate the usefulness of hyperpolarized (HP) 129Xe gas MRI for regional assessment of pulmonary function.
CONDITIONS
Official Title
Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy volunteers with no diagnosed lung conditions
- Diagnosed pulmonary dysfunction confirmed by a physician for lung disease subjects
- No acute worsening of lung function in the past 30 days for lung disease subjects
- Ability to read and understand English or Spanish
- Age between 18 and 80 years
You will not qualify if you...
- MRI contraindicated based on MRI screening questionnaire
- Pregnancy or lactation
- Unable to fit into the 129Xe vest coil used for MRI
- Unable to hold breath for 15-16 seconds
- Unlikely to comply with imaging instructions
- Oxygen saturation less than 88% on room air or supplemental oxygen
- Cognitive deficits preventing consent
- Institutionalization
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Kansas Medical Center
Kansas City, Kansas, United States, 66160
Actively Recruiting
Research Team
C
Cristal Monge
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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