Actively Recruiting

Phase 1
Age: 18Years - 80Years
All Genders
NCT04772456

Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

Led by University of Maryland, Baltimore · Updated on 2025-09-22

5

Participants Needed

1

Research Sites

385 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to examine the safety and feasibility of performing hyperpolarized metabolic MRI in the diagnosis of brain tumor. This study will also assess the accuracy of hyperpolarized metabolic MRI to diagnose intermediate to patients with infiltrating gliomas and examine the added utility of metabolic MRI over standard MRI imaging The FDA is allowing the use of hyperpolarized \[1-13C\] pyruvate (HP 13C-pyruvate) in this study. Up to 5 patients may take part in this study at the University of Maryland, Baltimore (UMB).

CONDITIONS

Official Title

Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a new brain lesion suspected to be infiltrating gliomas or with prior history of infiltrating glioma scheduled for tumor biopsy or resection
  • Age between 18 and 80 years
  • Able to undergo contrast-enhanced MRI
  • Negative serum pregnancy test
Not Eligible

You will not qualify if you...

  • Unable to undergo MRI scan
  • Unable to receive IV contrast due to severe reaction or kidney problems

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rosy Njonkou Tchoquessi

Baltimore, Maryland, United States, 21201

Actively Recruiting

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Research Team

R

Rosy Njonkou Tchoquessi

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Hyperpolarized 13C-pyruvate Metabolic MRI With Infiltrating Gliomas | DecenTrialz