Actively Recruiting
Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and Toxicity
Led by M.D. Anderson Cancer Center · Updated on 2026-05-05
70
Participants Needed
1
Research Sites
230 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical research study is to learn if novel type of imaging scan called HP 129Xe MRI can help doctors identify and predict common side effects of radiation therapy. Rather than contrast-enhanced MRIs, the tracer (129Xe) will be inhaled rather than injected. The 129Xe tracer has not been FDA approved. Its use in this study is investigational.
CONDITIONS
Official Title
Hyperpolarized Xenon-129 Magnetic Resonance Imaging in Lung Cancer Patients Receiving Radiation Therapy for Investigating Radiation-response and Toxicity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to consistently hold breath for 10-12 seconds
- No history of pulmonary disorders for healthy controls
- Able to undergo MRI examination
- At least 18 years of age
- Biopsy proven diagnosis of lung cancer for patient cohort
- Receiving photon- or proton-based external beam radiotherapy
- Will receive follow-up at University of Texas MD Anderson Cancer Center
- Women and men with child-bearing potential agree to use adequate contraception during study
- Able to understand and willing to sign informed consent
You will not qualify if you...
- Unable to follow up at MD Anderson for routine care
- Unable or unwilling to give informed consent
- Relapsed disease or life expectancy less than 6 months
- Severe claustrophobia or active lung infection
- Pregnant women
- Under 18 years of age
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The University of Texas M. D. Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
J
Joshua Niedzielski, PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
3
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