Actively Recruiting

Early Phase 1
Age: 18Years +
All Genders
NCT06853145

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Led by University of Virginia · Updated on 2025-07-09

6

Participants Needed

1

Research Sites

134 weeks

Total Duration

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AI-Summary

What this Trial Is About

Idiopathic pulmonary fibrosis has a poor prognosis with limited treatment options. The Investigator hypothesize hyperpolarized Xe129-MRI can be performed in patients with IPF and repeated over time which will detect deficiencies related to perfusion in the lung.

CONDITIONS

Official Title

Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to provide informed consent
  • 18 years of age or older
  • Clinical diagnosis of idiopathic pulmonary fibrosis (IPF)
Not Eligible

You will not qualify if you...

  • Continuous oxygen use at home
  • Oxygen saturation less than 92% on the day of the MRI procedure
  • Pregnancy or lactation
  • Claustrophobia, inner ear implants, aneurysm or other surgical clips, metal foreign bodies in eye, pacemaker, or other contraindications to MRI
  • Implanted devices that cannot be verified as MRI compliant
  • History of congenital cardiac disease, chronic renal failure, or cirrhosis
  • Chest circumference greater than approximately 42 inches (coil size limit)
  • Inability to understand simple instructions or remain still for 10-15 seconds
  • Respiratory infection within 2 weeks prior to the MRI scan
  • History of myocardial infarction, stroke, or poorly controlled hypertension

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Snyder Building 480 Ray C. Hunt Drive

Charlottesville, Virginia, United States, 22908

Actively Recruiting

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Research Team

R

Roselove Asare, MA

CONTACT

C

Carol Bampoe, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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