Actively Recruiting
HyperSpectral Imaging in Low Grade Glioma
Led by Universitaire Ziekenhuizen KU Leuven · Updated on 2025-01-08
10
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
Sponsors
U
Universitaire Ziekenhuizen KU Leuven
Lead Sponsor
I
Imec
Collaborating Sponsor
AI-Summary
What this Trial Is About
Low grade glioma (LGG) is a slowly evolving, highly invasive intrinsic brain tumor displaying only subtle tissue differences with the normal surrounding brain, hampering the attempts to visually discriminate tumor from normal brain, especially at the border interface. This makes anatomical borders hard to define during early maximal resection, which is the initial treatment strategy. Therefore, innovative, robust and easy-to-use real-time strategies for intra-operative detection and discrimination of (residual) LGG tumor tissue would strongly influence on-site, surgical decision making, enabling a maximal extent of resection. To validate this approach hyperspectral imaging (HSI) - using a SnapScan HSI-Camera (IMEC), stably mounted on an OPMI Pentero 900 microscope (Zeiss) - will be used to generate spectral imaging data patterns that discriminate in vivo low grade glioma tissue from normal brain both on the cortical and subcortical level.
CONDITIONS
Official Title
HyperSpectral Imaging in Low Grade Glioma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 63 18 years
- Radiologically suspected low grade glioma (newly diagnosed or recurrent)
- Scheduled for tumor resection at UZ Leuven
- Signed informed consent document prior to resection
You will not qualify if you...
- Children with age < 18 years
- If final pathology shows a diagnosis other than low grade glioma, data will be excluded from analysis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UZ Leuven
Leuven, Vlaams-Brabant, Belgium, 3000
Actively Recruiting
Research Team
S
Steven De Vleeschouwer, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DEVICE_FEASIBILITY
Number of Arms
1
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