Actively Recruiting
Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Gastric Cancer
Led by Ukrainian Society of Clinical Oncology · Updated on 2026-01-13
200
Participants Needed
1
Research Sites
521 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study investigates the outcomes of hyperthermic intraperitoneal chemoperfusion (HIPEC) in combination with curative-intent gastrectomy in resectable locally-advanced and limited-metastatic (low peritoneal cancer index) gastric cancer.
CONDITIONS
Official Title
Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- Histologically confirmed gastric adenocarcinoma
- ECOG performance status of 0 or 1
- Written informed consent to participate
- Medically and technically operable gastric tumor
- Tumors classified as T4a or T4b regardless of peritoneal cytology
- Cytologically positive peritoneal washings with any T and N status
- Adequate blood, liver, and kidney function (Hemoglobin > 120, Platelets > 150 x 10^9/L, ALT < 60, AST < 40, total bilirubin < 21 µmol/L, Creatinine clearance: males 90-140 ml/min, females 80-130 ml/min)
You will not qualify if you...
- Pregnancy or breastfeeding
- ECOG performance status 2 to 4
- Presence of any other malignancy
- Hypersensitivity to mitomycin or cisplatin
- Uncontrolled chronic diseases
- History of allergic reactions to cisplatin or mitomycin C
- Metastases beyond regional or peritoneal areas (e.g., liver, lungs, bone, brain, distant lymph nodes)
- Psychiatric illness or social situations impairing compliance
- Refusal to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Cancer Institute (NCI)
Kyiv, Ukraine
Actively Recruiting
Research Team
O
Oleksiy Dobrzhanskyi, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here