Actively Recruiting
Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation
Led by Fernando Bacal · Updated on 2026-05-06
74
Participants Needed
1
Research Sites
172 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this study is to evaluate if hypertonic saline solution can prevent or attenuate acute kidney injury after heart transplantation in the early postoperative phase.
CONDITIONS
Official Title
Hypertonic Saline Solution to Prevent Acute Kidney Injury After Heart Transplantation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hospitalized patients submitted to orthotopic heart transplantation (HT)
You will not qualify if you...
- Requirement of renal replacement therapy at the time of HT
- Requirement of extracorporeal membrane oxygenation (ECMO) before or immediately after HT
- Severe peri-operative mechanical complications
- Double transplant (e.g. heart-kidney or heart-lung)
- Hypernatremia (Na 6 145)
- Severe hyponatremia (Na 4 120)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Heart Institute, University of São Paulo.
São Paulo, Brazil
Actively Recruiting
Research Team
C
Ciro M Murad, MD
CONTACT
N
Núcleo Transplante Heart Institute / University of Sao Paulo
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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