Actively Recruiting
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas
Led by University of Wisconsin, Madison · Updated on 2026-01-28
30
Participants Needed
1
Research Sites
343 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research study is designed to find out if radiation therapy treatment prior to surgery is safe and effective to treat soft tissue sarcomas. 30 participants with soft tissue sarcoma will be enrolled and can expect to be on study for up to 5 years.
CONDITIONS
Official Title
Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biopsy proven soft tissue sarcoma of the extremity, trunk, or head and neck
- No prior sarcoma-directed chemotherapy or radiotherapy
- Age 63 18 years
- Karnofsky performance status 63 60
- Able to understand and sign an informed consent
- Life expectancy greater than 12 weeks
- Hypofractionated or conventionally fractionated radiotherapy using Intensity Modulated Radiation Therapy (IMRT) deemed feasible and safe by treating physician
- Operable disease and medically fit for surgery with planned surgery within 5-14 days after completing radiation therapy
- Adequate bone marrow function (absolute neutrophil count > 500/mcL, hemoglobin > 8 g/dL, platelets > 50,000/mcL)
- Adequate renal function (creatinine clearance > 30 mL/min)
You will not qualify if you...
- Pregnant
- Unable to undergo imaging or positioning necessary for radiotherapy planning
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, United States, 53705
Actively Recruiting
Research Team
C
Cancer Connect
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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