Actively Recruiting

Phase 2
Age: 18Years - 75Years
All Genders
NCT06435260

Hypofractionated Radiotherapy +Chemotherapy+ Camrelizumab as Neoadjuvant Therapy for Pancreatic Cancer

Led by Hebei Medical University Fourth Hospital · Updated on 2025-06-26

30

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to assess surgical conversion rate and the immediate and long-term outcomes to patients who receive hypofractionated radiotherapy and AG combined with camrelizumab immunotherapy of Borderline Resectable/locally advanced pancreatic cancer.

CONDITIONS

Official Title

Hypofractionated Radiotherapy +Chemotherapy+ Camrelizumab as Neoadjuvant Therapy for Pancreatic Cancer

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years old, male or female
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 1
  • Tumor located in the pancreas
  • Pathological diagnosis of pancreatic ductal adenocarcinoma or acinar cell carcinoma
  • No distant metastasis present
  • Pancreatic tumor located more than 1 cm from the duodenum
  • Clinical assessment indicates locally advanced or borderline resectable pancreatic cancer
  • No history of immune system diseases, other cancers, myocarditis, coronary heart disease, cardiovascular or cerebrovascular diseases, thyroid dysfunction, liver or kidney diseases, psychiatric or infectious diseases, or systemic diseases other than those mentioned
  • Willing to participate, able to adhere to study procedures, and provide written informed consent
Not Eligible

You will not qualify if you...

  • Does not meet the above inclusion criteria
  • Poor cognitive ability or mental disorders preventing answering questions or completing questionnaires
  • Considered inappropriate for the study by investigators

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fourth Hospital of Hebei Medical University

Shijiazhuang, Hebei, China, 050011

Actively Recruiting

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Research Team

L

Li Peng

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Hypofractionated Radiotherapy +Chemotherapy+ Camrelizumab as Neoadjuvant Therapy for Pancreatic Cancer | DecenTrialz