Actively Recruiting
Hypofractionated Radiotherapy for Nasopharyngeal Carcinoma
Led by The Second Affiliated Hospital of Hainan Medical University · Updated on 2025-01-28
24
Participants Needed
1
Research Sites
149 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study was to evaluate the efficacy and safety of large fractionation radiotherapy in nasopharyngeal carcinoma patients, and to analyze whether Hypofractionated radiotherapy is not inferior to conventional radiotherapy.
CONDITIONS
Official Title
Hypofractionated Radiotherapy for Nasopharyngeal Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 75 years, male or female
- Performance status of 2 or less
- Diagnosed nasopharyngeal non-keratonic carcinoma confirmed by pathology
- At least one evaluable lesion according to Recist1.1 criteria
- Expected survival of 6 months or more
- Normal functioning of main organs with blood counts meeting specific thresholds: hemoglobin ≥ 100 g/L, white blood cells ≥ 3×10^9/L, absolute neutrophil count ≥ 1.5×10^9/L, platelets ≥ 100×10^9/L
- Liver function within limits: bilirubin < 1.5 times normal, ALT and AST < 2.5 times normal, GPT ≤ 1.5 times normal
- Kidney function with serum creatinine ≤ 1 times normal and creatinine clearance > 60 ml/min
- Good blood clotting function with INR or prothrombin time ≤ 1.5 times normal
- Normal myocardial enzyme levels
- Willing and able to give informed consent and comply with study procedures
You will not qualify if you...
- Pregnant or breastfeeding women
- Severe health conditions preventing tolerance or completion of radiotherapy
- Contraindications to MRI
- Presence of a second primary cancer
- Severe complications such as hypertension, coronary heart disease, mental illness, or history of allergies
- Participation in any other research study within 4 weeks prior to enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital of Hainan Medical University
Haikou, Hainan, China, 570311
Actively Recruiting
Research Team
Y
yuecan zeng, doctor
CONTACT
J
junnv xu, doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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