Actively Recruiting

Age: 18Years - 99Years
All Genders
NCT06332404

Hypoglossal Nerve Stimulation Therapy in Patients With Obstructive Sleep Apnea: Belgian Registry

Led by University Hospital, Antwerp · Updated on 2025-09-15

225

Participants Needed

2

Research Sites

519 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Hypoglossal nerve stimulation (HNS) therapy (Inspire system) is intended for the treatment of patients with moderate to severe obstructive sleep apnea (OSA) who cannot be effectively treated with the first-line treatment options. Recently, the request for reimbursement of the Inspire system in Belgium was approved. The aim is to create a multi-center registry of OSA patients that are treated with HNS (Inspire system) within routine clinical care in Belgium.

CONDITIONS

Official Title

Hypoglossal Nerve Stimulation Therapy in Patients With Obstructive Sleep Apnea: Belgian Registry

Who Can Participate

Age: 18Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient implanted with or receiving the Inspire HNS system and able to give informed consent
  • At least 18 years old at the time of implantation
  • Moderate to severe obstructive sleep apnea (AHI between 15 and 65 events per hour)
  • Failed, not tolerated, or contraindicated for CPAP and/or mandibular advancement device therapy
  • No complete concentric collapse of the soft palate during Drug-Induced Sleep Endoscopy (DISE)
Not Eligible

You will not qualify if you...

  • Body mass index (BMI) greater than 32 kg/m²
  • Mixed and central apnea-hypopnea index more than 25% of total AHI
  • Complete concentric collapse at the soft palate or anatomical issues impeding HNS function
  • Severely impaired neurological control over the upper airway
  • Pregnancy
  • Surgery on the soft palate within 3 months before implantation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

Antwerp University Hospital

Edegem, Antwerp, Belgium, 2650

Actively Recruiting

2

AZ Sint-Jan Brugge

Bruges, West-Vlaanderen, Belgium, 8000

Actively Recruiting

Loading map...

Research Team

D

Dorine Van Loo, MSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here