Actively Recruiting

Age: 18Years - 100Years
All Genders
Healthy Volunteers
NCT05793853

Hypoparathyroidism Natural History Study

Led by Columbia University · Updated on 2025-12-16

106

Participants Needed

1

Research Sites

222 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective three-year natural history study of adults with hypoparathyroidism. The goal is to monitor patients with hypoparathyroidism to define end-organ damage in the context of the disease. The study objectives are to: 1. Build a prospective cohort of patients to study HPT-associated end-organ damage. 2. Determine end-organ physiologic consequences of HPT. 3. Elucidate determinants of HPT-associated end-organ damage. Funding Source - FDA OOPD

CONDITIONS

Official Title

Hypoparathyroidism Natural History Study

Who Can Participate

Age: 18Years - 100Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability and willingness to fully comply with study procedures and restrictions
  • Ability to voluntarily provide written, signed, and dated informed consent
  • Male or female 18 years of age or older with hypoparathyroidism, including all subtypes such as surgical, autoimmune, genetic, infiltrative, mineral deposition, metastatic, radiation, and idiopathic
  • Diagnosis of hypoparathyroidism confirmed by historic low calcium and low serum PTH levels on two occasions
  • All treatment regimens allowed, including calcium, vitamin D forms, magnesium, phosphate binders, thiazides, and PTH-like drugs
Not Eligible

You will not qualify if you...

  • Functional hypoparathyroidism
  • Transient hypoparathyroidism
  • Pseudohypoparathyroidism
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Columbia University Medical Center - Harkness Pavillion

New York, New York, United States, 10032

Actively Recruiting

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Research Team

N

Noelle Texeira

CONTACT

A

Aastha Mehta

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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