Actively Recruiting
Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia
Led by National and Kapodistrian University of Athens · Updated on 2026-04-20
100
Participants Needed
1
Research Sites
50 weeks
Total Duration
On this page
Sponsors
N
National and Kapodistrian University of Athens
Lead Sponsor
A
Attikon Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study investigates if the Hypotension Prediction Index (HPI) combined with the Assisted Fluid Management (AFM) software can improve perioperative hemodynamic management in adult patients undergoing general anesthesia. The main question is : Does the HPI and AFM software reduce the incidence and duration of intraoperative hypotension? Does the HPI and AFM software optimize fluid and vasopressor administration? Does the HPI and AFM software improve perioperative outcomes? Participants will be randomly allocated to either an experimental group receiving goal directed hemodynamic therapy guided by HPI and AFM or a control group receiving conventional hemodynamic management.
CONDITIONS
Official Title
Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Surgery under general anesthesia expected to last more than 2 hours
- Invasive arterial pressure monitoring during surgery
- Target mean arterial pressure (MAP) of at least 65 mm Hg during surgery
- Written informed consent obtained before surgery
- American Society of Anesthesiologists (ASA) Physical Status classification of 4 or lower
You will not qualify if you...
- Planned target mean arterial pressure (MAP) other than 65 mm Hg
- Severe low blood pressure before surgery (MAP below 65 mm Hg)
- Severe heart failure, such as left ventricular ejection fraction below 20%
- Emergency surgery
AI-Screening
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Trial Site Locations
Total: 1 location
1
2nd University Department of Anesthesiology, Attikon University Hospital
Athens, Attica, Greece, 12462
Actively Recruiting
Research Team
G
Georgia Ntalamagka, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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