Actively Recruiting

Phase Not Applicable
Age: 70Years +
All Genders
NCT04831957

Hypothyroidism After the TAVI Procedure in Elderly Patients

Led by Universitair Ziekenhuis Brussel · Updated on 2024-12-09

20

Participants Needed

1

Research Sites

1535 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Aortic stenosis is highly prevalent in advancing age. The prognosis of this disease has dramatically changed with the surgical replacement of the aortic valve and the trans catheter aortic valve re-placement (TAVI). The TAVI procedure is also successful in octogenarians and frail patients. However, the evaluation before the TAVI procedure requires a high dosage of iodinated contrast agent with, consequently, an increased risk for thyroid dysfunction. The primary endpoint of this study is to assess, prospectively, the incidence and the predictive factors (underlying thyroid disease, medication, food preservative, topical antiseptics) of hypothyroidism after a TAVI procedure. The secondary endpoint is the influence of the occurrence of hypothyroidism after the TAVI procedure on the geriatric assessment.

CONDITIONS

Official Title

Hypothyroidism After the TAVI Procedure in Elderly Patients

Who Can Participate

Age: 70Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed and dated written informed consent given before any study procedures
  • Male or female patients aged 70 years or older
  • Patients scheduled to undergo a TAVI procedure
Not Eligible

You will not qualify if you...

  • No signed, dated, and written informed consent obtained
  • Known thyroid dysfunction such as Basedow or Hashimoto disease
  • Current use of Lithium, Strumazol, or recent treatment with radioactive iodine

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UZ brussel

Brussels, Belgium, 1090

Actively Recruiting

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Research Team

N

nathalie Compté, Dr, PhD

CONTACT

B

Bert Bravenboer, Dr, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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