Actively Recruiting
The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study
Led by University of Oklahoma · Updated on 2026-04-28
240
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The hysterosalpingogram (HSG) is the gold standard of assessing fallopian tube patency and involves the placement of a transcervical catheter to allow for instillation of radio-opaque dye into the uterine cavity and fallopian tubes which are then imaged with abdominal x-ray. A common side effect of the instillation of dye is the uterine cramping, which is both uncomfortable for the patient as well as can cause iatrogenic proximal occlusion of the fallopian tubes. Proximal tubal obstruction is often not representative of true tubal obstruction but is rather an artifact of the test. Prior studies measuring the perceived pain and cramping during HSG have been conducted which have shown reduced pain scores and decreased uterine cramping when warmed contrast dye is used. The researchers propose that the use of warmed contrast media during HSG will be correlated with decreased pain scores and fewer cases of proximal tubal occlusion in women with otherwise normal uterine anatomy.
CONDITIONS
Official Title
The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women ages 18-45 undergoing tubal assessment via HSG
You will not qualify if you...
- History of fibroids
- History of pelvic inflammatory disease or sexually transmitted infections including gonorrhea, chlamydia, or trichomonas
- History of surgically diagnosed endometriosis or suspected endometriosis on ultrasound
- History of ectopic pregnancy or 3 or more biochemical pregnancies or pregnancy of unknown location
- History of tubal or ovarian surgery
- History of known Mullerian anomaly
- History of pelvic surgery including appendectomy
- Allergy to iodine-based contrast media
- History of prior abnormal fallopian tubes on HSG
- History of ultrasound showing hydrosalpinx (unilateral or bilateral)
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of Oklahoma Health Center
Oklahoma City, Oklahoma, United States, 73104
Actively Recruiting
Research Team
C
Christy Zornes, MHR
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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