Internet-Based Cognitive Behavioral Therapy Compared to Usual Depression Treatment for Seniors Over 65 in Primary Care

What this Trial Is About

Researchers are evaluating internet cognitive behavioural therapy iCBT for older adults over 65 years with mild to moderate depression in primary care settings. This study compares iCBT with the usual depression treatments provided at primary care centres, aiming to see if iCBT can reduce depressive symptoms, improve quality of life, and increase daily functioning over a period of 36 months. Participants will be randomly assigned to either the iCBT program or treatment as usual TAU. The iCBT program lasts 10 to 12 weeks, with weekly therapist or nurse contact via email or phone. The control group receives standard depression care according to Swedish guidelines, which may include self-help, face-to-face therapy excluding iCBT, or antidepressant medication. The study design reflects typical primary care practice to ensure real-world applicability. During the study, participants will be followed up at 3, 6, 12, 24, and 36 months to assess changes in depressive symptoms, quality of life, work ability, daily functioning, and social participation. Assessments include standardized questionnaires such as the Montgomery and Asberg Depression Rating Scale MADRS-S and the EQ-5D quality of life scale. Focus group interviews with patients and staff will explore experiences with iCBT. The total participation time may last up to three years with regular evaluations throughout.

iCBT for Seniors With Depression in Primary Care