Actively Recruiting
ICG (Indocyanine Green) Imaging Fluorescence Technology in Surgical Treatment of Advanced Gastric Cancer
Led by Niguarda Hospital · Updated on 2026-04-16
360
Participants Needed
1
Research Sites
256 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The iGreenGO Study aims to investigate whether the intraoperative application of NIR/ICG technology is associated with a change in the surgical conduct (CSC) during curative-intent gastrectomy with D2 lymphadenectomy in a cohort of Western patients affected by AGC. The preoperative clinical variables potentially associated with CSC will be also investigated
CONDITIONS
Official Title
ICG (Indocyanine Green) Imaging Fluorescence Technology in Surgical Treatment of Advanced Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
Inclusion criteria
- Age ≥ 18 years old
- Preoperative histologically proven adenocarcinoma of the upper, middle or lower part of the stomach.
- Advanced disease (Staged cT2-T4a, N0-3;M0 according to 8th edition of the AJCC TNM Staging System) at diagnosis, in which resection can be safely achieved by distal or total gastrectomy with D2 lymphadenectomy via a minimally invasive (laparoscopic or robotic) approach, either as first treatment or after neoadjuvant treatment
- No distant metastasis, no direct invasion of pancreas, spleen or other organs nearby in the preoperative and intraoperative examinations
- Written informed consent
Exclusion criteria
- Women during pregnancy or breast-feeding
- History of previous upper abdominal surgery (laparoscopic cholecystectomy will be allowed)
- History of previous gastrectomy, endoscopic mucosal resection or endoscopic submucosal dissection
- History of allergy to iodine agents
- Cancer located at the esophago-gastric junction (Siewert I, II, III tumors 29)
- Patients candidates to transthoracic esophagectomy, transhiatal extended gastrectomy or proximal gastrectomy
- History of previous neoadjuvant chemotherapy (except perioperative chemotherapy for gastric cancer) or radiotherapy
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
AI-Screening
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Trial Site Locations
Total: 1 location
1
ASST GOM Niguarda
Milan, Italia, Italy, 20162
Actively Recruiting
Research Team
P
Pietro M Lombardi, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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