Actively Recruiting
The ICU LIBERATION Study
Led by Japanese Society for Early Mobilization · Updated on 2024-09-19
1000
Participants Needed
1
Research Sites
447 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Acute respiratory distress syndrome (ARDS) is a condition associated with hypoxemia due to noncardiogenic causes and results in high mortality. However, the epidemiology and treatment strategy for ARDS may have changed significantly due to the accumulation of a large body of knowledge, following the two-year pandemic of the novel coronavirus (SARS-CoV-2) of which the primary manifestation is ARDS. To improve the quality of ICU care that patients receive after admission to the ICU, a variety of academic societies, including the Japanese Society of Intensive Care Medicine and the Society of Critical Care Medicine, are currently developing evidence-based guidelines and consensus guidelines and statements regarding ABCDEF bundles, nutritional therapy, ICU diary. The ABCDEF bundle, nutritional therapy, and ICU diary have been developed and are being promoted for implementation in hospitals around the world. The implementation of evidence-based ICU care is strongly recommended, especially for patients with acute respiratory distress syndrome who frequently require ventilators to maintain their lives, because their patient outcomes are worse than those who were admitted to ICU with other causes. However, there is still little evidence on how the quality of ICU care (compliance rate) correlates with patient prognosis and outcomes, and there are currently no clear goals or indicators for the ICU care we should develop. This study aims to investigate the epidemiology and treatments given to the patients and evaluate the implementation of evidence-based ICU care and its association with the outcomes of patients with acute respiratory distress syndrome admitted to the ICU. The contents of mechanical ventilation settings, respiratory conditions, and the evidence-based ICU care, such as analgesia, sedation, rehabilitation, and nutrition, given to the patients will be collected in a daily basis. Aim 1: Epidemiology Aim 2: Treatments Aim 3: Evidence-based ICU care Aim 4: ARDS related Post Intensive Care Syndrome
CONDITIONS
Official Title
The ICU LIBERATION Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients on an invasive or non-invasive ventilator within 24 hours of ICU admission
- Patients expected to be on an invasive and/or non-invasive ventilator for more than 48 hours in total
- Patients diagnosed with acute respiratory distress syndrome (ARDS) within 24 hours of ICU admission
You will not qualify if you...
- Patients younger than 16 years old
- Patients with terminal conditions at the time of ICU admission
- Patients admitted to the ICU with a terminal care policy or expected to be admitted with one within 24 hours of ICU admission
- Patients who have refused to have their clinical data used in research
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
LIBERATION Study Research Office
Tokyo, Japan, 102-0073
Actively Recruiting
Research Team
K
Kensuke Nakamura, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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