Actively Recruiting
Idebenone for the Preventive Treatment of Migraine
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2025-05-15
180
Participants Needed
1
Research Sites
212 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Idebenone improves energy metabolism similarly to Coenzyme Q10, which is effective in migraine prophylaxis. The investigators compare idebenone (90 mg/day, 270 mg/day) and placebo in 180 migraine patients in a double-blind, randomized, placebo-controlled, multicenter trial to study whether Idebenone is superior to placebo in the prevention of episodic migraine with or without aura.
CONDITIONS
Official Title
Idebenone for the Preventive Treatment of Migraine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of episodic migraine
- Age between 18 and 65 years
- Meets International Headache Society criteria for episodic migraine with or without aura with at least 1 year history
- Experiences two to eight migraine attacks per month with 5 days per month of interval headaches
- Does not overuse acute anti-migraine medication
- No use of other migraine prevention medication for at least 3 months
- No serious organic or psychiatric disease
- Women must use contraceptive protection
You will not qualify if you...
- Diagnosis of chronic migraine
- Previously stopped idebenone due to side effects
- Currently taking idebenone or took idebenone within 14 days before enrollment
- Continuous headaches
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Kaiming Liu
Hangzhou, Zhejiang, China, 370001
Actively Recruiting
Research Team
K
Kaiming Liu, MD & PHD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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