Actively Recruiting
Identification of Biomarkers of Risk for Pre-neoplastic and Neoplastic Lesions for the Development of Gastric Cancer
Led by Centro di Riferimento Oncologico - Aviano · Updated on 2026-02-02
192
Participants Needed
1
Research Sites
88 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Investigator propose the implementation of circulating biomarker monitoring, focusing on molecules related to the progression of gastric atrophy and/or associated with gastric cancer. Monitoring these biomarkers will provide gastroenterologists with timely information on individuals at risk and, if values worsen during follow-up, will alert physicians observing these patients to evaluate them. This monitoring will be offered to individuals who contact the IBO (Immunopatologia e Biomarcatori Oncologici) Unit at CRO (Centro di Riferimento Oncologico) in Aviano requesting an assessment of gastric function through pepsinogen and G17 gastrin level testing. Monitoring these biomarkers will provide a dynamic analysis of patients' gastric status, allowing for timely intervention in case of deviations from normal values. This proactive approach is important for the preventive management of gastric diseases, particularly for the diagnosis and monitoring of gastric atrophy and gastric cancer. The IBO unit of the CRO in Aviano, together with the pathological anatomy and clinical units of gastroenterology, medical oncology, and surgery, will play a role in coordinating and implementing this monitoring program, thus contributing to the promotion of gastric health and the prevention of associated diseases.
CONDITIONS
Official Title
Identification of Biomarkers of Risk for Pre-neoplastic and Neoplastic Lesions for the Development of Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged over 18 years
- Able to understand, accept, and sign the informed consent form for the study
- Able to understand, accept, and sign the consent form for data processing
- Able to understand, accept, and sign the consent form for collection of a serum sample for research
- Fasting patients who have requested a pepsinogen test or gastroscopy, or who have gastric cancer prior to treatment
- Fasting subjects with suspected pre-neoplastic or neoplastic gastric lesions or who have requested a pepsinogen test and have available endoscopic examination data
You will not qualify if you...
- Under 18 years of age
- Pregnant women
- Patients with another malignant cancer diagnosed in the last 5 years
- Unable to understand, accept, and sign the consent form for data processing
AI-Screening
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Trial Site Locations
Total: 1 location
1
Centro di Riferimento Oncologico (CRO) di aviano-IRCCS
Aviano, Pordenone, Italy, 33081
Actively Recruiting
Research Team
V
Valli De Re, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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